Vampire Hunter D is based on Hideyuki Kikuchi's novel series of the same title. Hideyuki Kikuchi personally selected Saiko Takaki as the artist for the manga adaptation.
The series had seven volumes published in English as Hideyuki Kikuchi's Vampire Hunter D by Digital Manga Publishing, in print from November 25, 2007 to May 29, 2013, and digitally from June 8, 2009 to May 13, 2013. It has also been published in German, French, Finnish, Spanish, Lithuanian and Russian.