An anime adaptation was planned for Alive: Saishuu Shinkateki Shounen and was to be produced by anime studio Gonzo, but the production was cancelled in 2010 when the studio was delisted from the Tokyo Stock Exchange.
The series was published digitally in English as Alive: The Final Evolution by Kodansha Comics USA from July 26, 2016 to August 29, 2017. Prior to this, Del Rey Manga had published 8 printed volumes from July 31, 2007 to November 24, 2009 before publication was discontinued.