Rather than directly adapting the source material like the previous film, Ghost in The Shell 2: Innocence instead is based on an idea present in one of the subplots from the original manga. Alongside the movie, there was a book published that served as a prequel to Innocence called After the Long Goodbye.
Ghost in the Shell 2: Innocence was nominated for the Palme d'Or at the Cannes Film Festival in 2004, and is so far the only anime to have been nominated for this prestigious award.