Oooku (Ōoku: The Inner Chambers) - Yoshinaga, Fumi

In Edo period Japan (1603 to 1868), a strange new disease called the Redface Pox has begun to prey on the country's men. Within eighty years of the first outbreak, the male population has fallen to a quarter of the total female population. Women have taken on all the roles traditionally granted to men, even that of the Shogun. The men, precious providers of life, are carefully protected and the most beautiful of the men are sent to serve in the Shogun's Inner Chambers.

(Source: VIZ Media)

Oooku won an Excellence Prize at the 2006 Japan Media Arts Festival, the Tezuka Osamu Cultural Grand Prize in 2009, and the 56th Shogakukan Manga Award in shoujo manga category in 2011. The series also received special prize at The Japanese Association of Feminist Science Fiction and Fantasy's 5th annual Sense of Gender awards in 2005, a live-action film based on the series was screened in 2010, and it received a two television drama adaptations in 2012.
Oooku has been published in English as Ōoku: The Inner Chambers by VIZ Media under the VIZ Signature imprint since August 18, 2009.